Nuclear magnetic resonance (NMR) is a multipurpose tool for observing chemical and biological processes. Its non-invasive nature allows for materials analysis in various external conditions. Generally, a strong magnetic field with a magnitude of more than 1 Tesla is used to achieve good signal strength and high resolution.
In medical applications of magnetic resonance contrast agents are often used to facilitate higher image contrast for better analysis. Contrast agents work by having a quicker longitudinal relaxation time T\(_{1}\) which results in higher image contrast. Currently a new contrast agent – fumaric acid, is gaining attention and shows potential. By looking into fumaric acid and its isotopomers the aim is to find desirable isotopomer which has a short relaxation time. Short relaxation time is essential for contrast agents in magnetic resonance imaging. This means that extensive research is required to fully understand this material and its properties in various external conditions[1].
In this work I will discuss the properties of longitudinal relaxation time T\(_{1}\) of fumaric acid in different temperatures and different external magnetic fields. It was observed that \(^{1}\)H relaxation times were similar but isotopomers with \(^{13}\)C displayed more complex data. Such information would allow for careful evaluation of the potential use in medicine.